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VOLTAGE-GATED SODIUM CHANNEL BETA-1 SUBUNIT
Descriptors Found:
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DeCS
Descriptor
English
:
Voltage-Gated Sodium Channel beta-1 Subunit
Descriptor
Spanish
:
subunidades beta-1 de los canales del sodio dependientes de voltaje
Descriptor
Portuguese
:
Subunidade beta-1 do Canal de Sódio Disparado por Voltagem
Synonyms
English
:
SCN1B Sodium Channel beta Subunit
Voltage Gated Sodium Channel beta 1 Subunit
Tree Number:
D12.776.157.530.400.875.750.960.100
D12.776.543.550.450.875.750.970.100
D12.776.543.585.400.875.750.970.100
D12.776.631.960.970.100
Definition
English
:
A voltage-gated
sodium
channel beta subunit abundantly expressed in SKELETAL MUSCLE; HEART; and BRAIN. It non-covalently associates with voltage-gated alpha subunits. Defects in the SCN1B gene, which codes for this beta subunit, are associated with generalized
epilepsy
with febrile
seizures
plus, type 1, and
Brugada syndrome
5.
Entry Combination - descr/qualif
English
:
Voltage-Gated Sodium Channel beta-1 Subunit
/
antagonists & inhibitors
use
Voltage-Gated Sodium Channel Blockers
Voltage-Gated Sodium Channel beta-1 Subunit
/
agonists
use
Voltage-Gated Sodium Channel Agonists
See Related
English
:
Brugada Syndrome
History Note
English
:
2013
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
54957
Unique Identifier:
D062547
Occurrence in VHL
:
Similar:
DeCS